Maalox versus cimetidine.

Antacid maintenance therapy in the prevention of duodenal ulcer relapse.

The effectiveness of antacid maintenance therapy in preventing duodenal ulcer (DU) relapse was investigated. Two hundred and fifty one asymptomatic patients with healed DU were stratified into smokers and non-smokers and randomised to receive for one year either placebo, or Maalox TC three tablets (81 mmol) at bedtime (hs), or Maalox TC three tablets in the morning plus three tablets at bedtime...

Cimetidine versus ranitidine in short term healing of duodenal ulcers.

Randomised crossover trial of tripotassium dicitrato bismuthate versus high dose cimetidine for duodenal ulcers resistant to standard dose of cimetidine.

Of 212 patients with duodenal ulcer treated with four weeks of one gram daily cimetidine, 25 had ulcers which underwent no reduction in size despite treatment. The effects of tripotassium dicitrato bismuthate (TDB) tablet four times a day or cimetidine 1.6 g daily on the healing of these cimetidine resistant ulcers were compared in a randomised crossover trial. Ten of 12 patients on tripotassiu...

Effect of Maalox and omeprazole on the bioavailability of trovafloxacin.

To determine the effect of the concurrent administration of Maalox and omeprazole in the bioavailability of trovafloxacin (CP-99,219), an open, placebo-controlled, randomized, four-way crossover study was conducted in 12 healthy male volunteers. Each received treatments of three 100 mg trovafloxacin tablets in the morning 30 min after 30 mL of Maalox (A), 30 min after placebo (B), 2 h before 30...

Side effects of cimetidine.

Cimetidine, an H2 receptor antagonist, is widely used in the treatment of duodenal ulcer, ZollingerEllison Syndrome (Binder et al., 1978; Winship, 1978; Ippoliti et al., 1978; Gray et al., 1978; Lc Canthy, 1978) benign gastric ulcer, gastric erosions and oesophagitis (Freston, 1979; Frost et al., 1977; Englert et al., 1978). In human beings it has a circulating half life of disappearance of 123...